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Medical Center Luxury Homes For Sale

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Medical Center Luxury Homes Homes For Sale

$2,300,000
10 Beds ⋅ 9 Baths ⋅ 1870188 MLS ⋅ ACTIVE Status
Nestled in the heart of San Antonio, this stunning 7.74-acre estate offers a unique blend of history, luxury, and natural beauty. The centerpiece of the property is the historic Rosemont Mansion, a beautifully restored three-story home originally part of the Denman Estate. The estate features multiple buildings (1,694 sf office / 1,092 sf guest house / 1,360 sf garage apartment, pavilion and greenhouse) providing ample space and flexibility for various uses. This exceptional estate combines historical significance with modern amenities, making it an ideal investment for those seeking a luxurious private residence or a prestigious event venue. Don't miss the opportunity to own a piece of San Antonio's history.

7735 Mocking Bird Lane, San Antonio
$1,850,000
4 Baths ⋅ 2014690 MLS ⋅ NEW Status
9643 Huebner Road, San Antonio, TX 78240, a 5,924-square-foot medical office/business property strategically located in the heart of San Antonio's South Texas Medical Center. The property consists of two combined suites offering a versatile configuration for both investors and owner-users. Unit 103 encompasses approximately 3,614 square feet and features a traditional medical office layout with exam rooms, reception and patient waiting areas, administrative space, and private offices. Unit 102 offers approximately 2,310 square feet with a more open floor plan, providing flexibility for an owner-user, medical practice, or future tenant. The property currently features five exam rooms with sinks, six private office spaces, two reception/patient waiting areas, two administrative areas, a conference room, wet bar, break-room kitchenette, washer and dryer, one full bathroom, three half bathrooms, four HVAC units, and 8'+ ceilings. The property also provides 48 common parking spaces along with four private covered parking spaces. Located within the South Texas Medical Center, one of San Antonio's most significant healthcare, research, and medical employment hubs, the property benefits from proximity to major healthcare institutions including UT Health San Antonio, University Health, Methodist Healthcare, UT Health San Antonio MD Anderson Cancer Center, and the Audie L. Murphy VA Hospital. The Medical Center encompasses more than 900 acres, includes hundreds of medical offices, and supports more than 30,000 healthcare-related employees. (South Texas Medical Center. The Medical Center also attracts more than 5 million outpatient visitors and approximately 100,000 inpatient visitors annually, creating a substantial healthcare-oriented customer and employment base throughout the area. (South Texas Medical Center. 9643 Huebner Road offers an exceptional opportunity to acquire an established medical office property in a highly sought-after healthcare corridor, with existing medical infrastructure, flexible suite configurations, strong parking, and proximity to some of San Antonio's leading healthcare and research institutions.

9643 Huebner Rd Unit 103 & 102, San Antonio
$1,750,000
2 Beds ⋅ 3 Baths ⋅ 1891990 MLS ⋅ ACTIVE Status
Nestled within the prestigious gated community of Oak Hills Country Club, this exceptional 3.607-acre estate at 5351 Fredericksburg Road offers unparalleled luxury and privacy. The property features a stunning main residence built in 1922 and a charming guest house, both surrounded by majestic heritage live oaks and sprawling landscaped grounds. Enjoy sweeping views from multiple outdoor patios, perfect for entertaining or serene relaxation. Golf enthusiasts will delight in the private chipping greens and exclusive access to the community's gorgeous golf course, complemented by top-tier amenities including tennis courts, a clubhouse, and a sparkling pool. With ample attached garage space and a prime location in San Antonio's coveted Near Northwest located minutes from South Texas Medical Center, this estate combines sophisticated living with resort-style recreation, creating a rare opportunity for discerning buyers and developers.

5351 Fredericksburg, San Antonio
$1,720,000
2 Beds ⋅ 2 Baths ⋅ 1835400 MLS ⋅ ACTIVE Status
OCCUPIED & GATED. 2 Tracks, 1.29 Acres each, Total 2.58 Acres. Babcock Rd. Frontage 230 ft. Wide 491 ft. Length. Main House 2 bed, no closets, 2 bath, approx. 2076 sq. ft. Guest House 1 bed, 1 bath,1 living approx. 700 sq. ft. Property with Private Well Water, 2 RV Electric, Water and Sewer Hookups. Zoned Residential, Potential for Rezoning for Development.

6051 Babcock Rd, San Antonio
$1,280,000
3 Beds ⋅ 3 Baths ⋅ 2003644 MLS ⋅ PRICE CHANGE Status
LOCATION LOCATION LOCATION!! Truly a once-in-a-lifetime opportunity! Stunning Builder's Home! 3,451 square feet of luxurious living with nearly 100 feet of frontage on the 17th fairway at the championship Oak Hills Country Club. Conveniently located right in the heart of the San Antonio Medical Center area with easy access to IH-10, 410. Fulfill your dreams of living on the links! Just walk out your back door! Golf cart path directly to the club house with full pro shop, fitness center, hard and clay tennis courts, pickleball courts, junior Olympic sized swimming pool, fine dining and a wealth of programming! DON'T MISS THIS ONCE IN A LIFETIME OPPORTUNITY!

5401 Fredericksburg, San Antonio
$1,199,000
4 Beds ⋅ 2 Baths ⋅ 1912159 MLS ⋅ ACTIVE Status
Set on 6.78 private acres, this unique estate combines elegance, versatility, and privacy at an impressive scale. Enclosed by full perimeter/privacy fencing, the property offers an ideal setting for a luxury residence, boutique retreat, or private family compound, delivering both lifestyle and investment potential. In addition to two separate residences, the estate features an industrial warehouse for additional storage or creative use, a rear dwelling with renovation or rebuild potential, and a picturesque wedding canopy and gazebo-perfect for celebrations, and outdoor entertaining. A sweeping circular drive with dual gated entrances creates a grand sense of arrival, leading to oak-shaded grounds, multiple patios, and an expansive resort-style pool with hot tub, ideal for gatherings and leisure alike. Inside, both residences highlight timeless architectural details, including hardwood floors, stone fireplaces, and spacious living areas. A chef's kitchen provides the ideal space for entertaining or everyday comfort, while a private well ensures efficient and sustainable upkeep for the entire property. With its prime location, unmatched amenities, and endless possibilities, 6472 Whitby Rd is more than an estate-it's a destination of its own, offering an extraordinary opportunity to live, entertain, and create.

6472 Whitby, San Antonio
$1,160,000
4 Beds ⋅ 5 Baths ⋅ 1973283 MLS ⋅ ACTIVE Status
A rare offering in San Antonio's prestigious Oak Hills area, this architecturally significant residence brings a distinctly European sensibility to the heart of the Medical Center. Located within a private gated enclave with direct access to Oak Hills Country Club, the home combines striking contemporary design with the ease of a lock-and-leave lifestyle. Created by internationally recognized DDL Architects and SW11 International Custom Home Builders, the residence showcases soaring ceilings, dramatic steel beams, expansive walls of glass, and carefully curated materials, many sourced from Europe. Natural light fills the interiors, while mature oak trees, thoughtfully incorporated into the design, create a seamless connection between architecture and landscape. Designed for both grand entertaining and quiet retreat, the home opens to three intimate courtyard patios surrounded by tranquil water features, fire elements, and inviting gathering spaces. At its center is a year-round indoor smart pool, offering a private wellness experience rarely found in residential properties. The approximately 4,010-square-foot floor plan balances architectural sophistication with everyday comfort, creating spaces that feel equally suited for hosting guests, working remotely, or simply enjoying a peaceful evening at home. Private, secure, and remarkably low-maintenance, this residence is designed for those who value exceptional design, global sophistication, and the freedom to come and go with ease. Opportunities to acquire a home of this caliber and character are exceedingly rare. Experience one of San Antonio's most distinctive contemporary residences by scheduling your private tour today.

4139 Cliff Oaks St, San Antonio
$975,000
4 Beds ⋅ 3 Baths ⋅ 1946194 MLS ⋅ PRICE CHANGE Status
Stunning traditional home in an exclusive gated community next to Oak Hills Country Club (direct access via golf cart trail), this home offers plenty of space, comfort, and a prime location. Located in the Medical Center, this is the perfect medical professional estate. The open floor plan features high ceilings, crown molding, wood and stone floors, granite kitchen countertops, and two fireplaces. The spacious primary suite includes a sitting area and gorgeous bathroom with a balcony that boasts views of downtown fireworks. The study can easily serve as a fifth bedroom. Enjoy the enclosed backyard with an in-ground pool - perfect for relaxing or entertaining.

4123 Cliff Oaks, San Antonio
$914,000
4 Beds ⋅ 4 Baths ⋅ 2010322 MLS ⋅ PRICE CHANGE Status
$10,000 BUYER FLEX CASH for Interest Rate Buydown, Price Reduction or Closing Costs! Nearly 5,000 square feet of fully reimagined Oak Hills luxury: four oversized bedroom ensuites, each with a private full bath; a true two-up/two-down layout; soaring 20+ foot ceilings; and exceptional indoor-outdoor entertaining, all on nearly half an acre near the South Texas Medical Center. A dramatic great room is anchored by a towering statement fireplace. At the center of the home, the expansive kitchen offers abundant counter space, a breakfast bar and eat-in breakfast area with two 96 inch bifold glass doors on both sides open fully to two separate oversized decks one on each side, flooding the space with natural light and allowing gatherings to flow effortlessly from one deck through the kitchen to the other. The main-level primary retreat is a destination of its own, featuring a built-in electric fireplace with a dramatic floor-to-ceiling surround. The spa-inspired primary bath offers a dedicated dressing area, freestanding air-jetted tub and oversized walk-in shower, while the spectacular room-sized walk-in closet delivers exceptional storage. Master bedroom along with A second bedroom is downstairs; two additional ensuite bedrooms and a generous loft/game room are upstairs-an outstanding configuration for multigenerational living, extended guests or anyone who values privacy and flexibility. Additional highlights include a dedicated office, multiple living and dining areas, and a climate-controlled flex room within the garage, ideal for a studio, workshop, creative space home schooling or second office. A circular driveway, mature trees, brick-and-stucco exterior, attached two-car garage and dual outdoor decks complete this rare offering. Fully remodeled and created for grand-scale entertaining, 3919 Midvale delivers the space, flexibility and modern finishes rarely found in established Oak Hills. Priced below neighborhood value with lots of upgrades with room to add your personal touch.

3919 Midvale Dr, San Antonio
$850,000
5 Beds ⋅ 5 Baths ⋅ 2005634 MLS ⋅ ACTIVE Status
Positioned on a premier cul-de-sac lot in a quiet, highly desirable established neighborhood in Northwest San Antonio with no HOA, this exceptional fully renovated custom estate offers 4,126 square feet of refined living, featuring 5 bedrooms, 4 full baths, and 1 half bath complete with a 3-car garage, mature trees, and stunning city views. A timeless blend of elegance and sophistication, the home features a striking stucco and stone exterior, tile roof, brand new energy-efficient windows and new flooring. Inside, soaring ceilings, expansive living spaces, and abundant natural light create an atmosphere of understated luxury. Designed for grand entertaining and everyday comfort alike, the residence boasts multiple gathering spaces, including three spacious living areas, a formal dining room, a game room, a media room, and a dedicated mudroom for seamless daily organization. The gourmet kitchen is the heart of the home, featuring a new induction cooktop, double ovens, extensive cabinetry, generous prep space, and a large breakfast area. The versatile floor plan offers incredible flexibility: the main-level private guest suite features its own private entrance, making it ideal for multi-generational living or guests. Upstairs, discover a luxurious primary suite sanctuary with custom walk-in closet and a fully remodeled, spa-inspired bath. Tucked nearby is a hidden secret room that leads to an expansive rooftop deck with elevated views. Step outside to a true resort-style oasis. The sparkling in-ground pool is surrounded by lush landscaping, mature shade trees, expansive covered patios, and multiple outdoor entertaining areas designed for unforgettable gatherings. Wrought-iron fencing, specialty landscape lighting, and exceptional privacy further enhance the outdoor experience. Located within highly acclaimed Northside ISD and just minutes from premier shopping, dining, medical centers, major employers, and downtown San Antonio, this masterful reimagined residence offers a rare opportunity to own a legacy property with ultimate freedom, luxury, and space. A remarkable offering for the most discerning buyer!

9111 Rushing St, San Antonio
$799,000
4 Beds ⋅ 5 Baths ⋅ 1999496 MLS ⋅ ACTIVE Status
Private Gated Estate with Heated Pool & Guest House | Historic 1922 Adobe Meets Modern Luxury Rare opportunity to own just over an acre, gated luxury estate in historic Oakland Estates, minutes from the Medical Center. Situated on a private, tree-filled lot with mature oak trees, this one-of-a-kind property seamlessly blends the original 1922 adobe home with a thoughtfully designed contemporary addition, creating a residence unlike any other. Inside, you'll find three spacious living areas, windows that flood the home with natural light, and a beautifully updated gourmet kitchen featuring a gas cooktop, oversized island, double ovens, abundant cabinetry. The primary suite offers new luxury vinyl flooring, updated plumbing, and a private sunroom with new double-pane windows. Versatile interior spaces provide flexibility for a variety of uses and design styles. The resort-style backyard is designed for entertaining with a pool, completely resurfaced with a redesigned stone pool deck, outdoor shower, multiple patios, new turf, and expanded patio space surrounding the updated guest house. The detached guest house features a new HVAC system and water heater, offering endless flexibility for guests, multigenerational living, a home office, or studio. The one acre lot also features a separate large dog kennel/run. Additional highlights include a brand-new roof (July 2026), Florida room/workshop adjacent to primary suite, horses permitted, extensive landscaping improvements, and exceptional privacy-all while remaining minutes from shopping, dining, major highways, and San Antonio's Medical Center. A truly exceptional property combining history, luxury, and modern convenience.

10011 Southwell Road, San Antonio
$689,000
4 Beds ⋅ 3 Baths ⋅ 1971743 MLS ⋅ ACTIVE Status
Experience modern country living in this stunning new construction home situated on a spacious 1-acre lot. Designed with style and functionality in mind, this home features custom cabinetry, elegant granite countertops throughout, and luxurious walk-in showers. The open-concept layout offers contemporary finishes and quality craftsmanship at every turn. Step outside to enjoy the large covered patio-perfect for entertaining, relaxing, or taking in the peaceful surroundings. With modern design, premium upgrades, and plenty of room to spread out, this beautiful new build is ready to welcome you home.

6471 Hollyhock Rd, San Antonio
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