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Medical Center - San Antonio Homes For Sale

$2,995,000
6 Beds ⋅ 8 Baths ⋅ 1948059 MLS ⋅ ACTIVE Status
Tucked behind private gates on 6.5 acres of beautifully manicured grounds, this exceptional French-inspired estate offers a rare blend of timeless elegance and modern luxury in an unparalleled location. A winding, tree-lined drive welcomes you, leading past lush gardens and a picturesque 2.5-acre lake, setting the stage for this remarkable residence. Designed with influences from the French countryside, the home boasts soaring ceilings, graceful archways, and expansive windows that frame breathtaking views

7 Lazy Hollow, San Antonio
$2,300,000
1909466 MLS ⋅ BACK ON MARKET Status
This 7.4 acre property in the heart of San Antonio features multiple buildings - the historic Rosemont Mansion, a 1,694 sf office / 1,092 sf guest house / 1,360 sf garage apartment, pavilion and greenhouse - providing ample space and flexibility for various uses. This exceptional property combines historical significance with modern amenities, making it an ideal investment for those seeking a private residence, event venue or corporate location.

7735 Mockingbird Ln, San Antonio
$2,300,000
10 Beds ⋅ 9 Baths ⋅ 1870188 MLS ⋅ BACK ON MARKET Status
Nestled in the heart of San Antonio, this stunning 7.74-acre estate offers a unique blend of history, luxury, and natural beauty. The centerpiece of the property is the historic Rosemont Mansion, a beautifully restored three-story home originally part of the Denman Estate. The estate features multiple buildings (1,694 sf office / 1,092 sf guest house / 1,360 sf garage apartment, pavilion and greenhouse) providing ample space and flexibility for various uses. This exceptional estate combines historical significance with modern amenities, making it an ideal investment for those seeking a luxurious private residence or a prestigious event venue. Don't miss the opportunity to own a piece of San Antonio's history.

7735 Mocking Bird Lane, San Antonio
$1,720,000
2 Beds ⋅ 2 Baths ⋅ 1835400 MLS ⋅ ACTIVE Status
OCCUPIED & GATED. 2 Tracks, 1.29 Acres each, Total 2.58 Acres. Babcock Rd. Frontage 230 ft. Wide 491 ft. Length. Main House 2 bed, no closets, 2 bath, approx. 2076 sq. ft. Guest House 1 bed, 1 bath,1 living approx. 700 sq. ft. Property with Private Well Water, 2 RV Electric, Water and Sewer Hookups. Zoned Residential, Potential for Rezoning for Development.

6051 Babcock Rd, San Antonio
$1,650,000
1997121 MLS ⋅ ACTIVE Status
8931 Wurzbach Road is a rare opportunity to acquire a 5,971 SF freestanding commercial building situated on 0.855 acres in one of San Antonio's most established and high-traffic commercial corridors. Zoned C-3 General Commercial, the property offers exceptional flexibility for a wide range of retail, restaurant, medical, office, entertainment, and service-oriented uses. Formerly operated as a restaurant, the property features ample on-site parking with space for a drive-thru, strong visibility along Wurzbach Road, and convenient access to Interstate 10 within half a mile. The site benefits from a strategic position near the South Texas Medical Center, one of the largest healthcare hubs in Texas, as well as major employers and institutions, including USAA Headquarters. Surrounded by dense residential neighborhoods, established retail centers, hotels, and medical facilities, the property offers access to a substantial consumer base and workforce population. The location provides excellent connectivity to Fredericksburg Road, Loop 410, Downtown San Antonio, and Northwest San Antonio, making it well-suited for owner-users seeking a central location or investors pursuing repositioning and redevelopment opportunities.

8931 Wurzbach Rd, San Antonio
$1,300,000
3 Beds ⋅ 3 Baths ⋅ 2003644 MLS ⋅ ACTIVE Status
LOCATION LOCATION LOCATION!! Truly a once-in-a-lifetime opportunity! Stunning Builder's Home! 3,451 square feet of luxurious living with nearly 100 feet of frontage on the 17th fairway at the championship Oak Hills Country Club. Conveniently located right in the heart of the San Antonio Medical Center area with easy access to IH-10, 410. Fulfill your dreams of living on the links! Just walk out your back door! Golf cart path directly to the club house with full pro shop, fitness center, hard and clay tennis courts, pickleball courts, junior Olympic sized swimming pool, fine dining and a wealth of programming! DON'T MISS THIS ONCE IN A LIFETIME OPPORTUNITY!

5401 Fredericksburg, San Antonio
$1,200,000
5 Beds ⋅ 6 Baths ⋅ 1990661 MLS ⋅ ACTIVE Status
A rare opportunity to own and revitalize an expansive estate in one of San Antonio's most coveted corridors. Offering 6,068 square feet of living space in a truly funcitonal tri-level home with lower level walkout access. The home showcases an exceptional combination of scale, privacy, architectural character, and versatility. The property features controlled access, a spacious backyard and gazebo, mature trees, and elevator access/entry. The third garage is complemented by an attached casita, offering flexibility for guests, extended family, or private accommodations. Inside, the home's generous living spaces showcase characteristics of its' generation, including wood coffered ceilings and a large living area with an adjoined wet bar, perfect for entertainment. Stone accents and wooden built-ins offer tremendous potential for restoration, personalization, or transformation. As a whole, 9218 Callaghan Rd. presents a unique opportunity to create something truly exceptional in a highly desirable San Antonio location. An incredible canvas for those with an exceptional vision. Estate offered AS-IS.

9218 Callaghan Rd, San Antonio
$1,200,000
1919146 MLS ⋅ ACTIVE Status
Exceptional Opportunity to Acquire a Commercial Property in the San Antonio Medical Center! Building & Zoning: Remodeled shell building (2025) with updated zoning to Neighborhood Commercial (NC) allowing for flexible uses Lot size: ~1 Acre with ingress from and egress to Old Babcock Rd, Building Sizes: 3000 sq. ft. shell building with utilities in place and a 400 sq ft storage two-story storage building Approved Plans: City-approved construction plans, new survey, and platting included Location: Prime area near major hospitals, USAA, UT San Antonio, La Cantera, The Rim, Medical Drive, local businesses, and key highways Potential Uses: Ideal for a variety of commercial ventures such as:-Medical or Dental Office-Law Firm or Professional Office-Coffee Shop, Bakery, Grocery, or QSR-Veterinary Clinic or Pet Grooming Features & Upgrades: 10-space asphalt parking lot completed (October 2025) Additional Options: Available for long-term lease, as well. This property offers flexibility, visibility, and is in a strategic location dense with residential, national retailers and restaurants, medical providers, and more, making it a perfect investment opportunity for a wide range of uses.

6395 Old Babcock, San Antonio
$1,199,000
4 Beds ⋅ 2 Baths ⋅ 1912159 MLS ⋅ BACK ON MARKET Status
Set on 6.78 private acres, this unique estate combines elegance, versatility, and privacy at an impressive scale. Enclosed by full perimeter/privacy fencing, the property offers an ideal setting for a luxury residence, boutique retreat, or private family compound, delivering both lifestyle and investment potential. In addition to two separate residences, the estate features an industrial warehouse for additional storage or creative use, a rear dwelling with renovation or rebuild potential, and a picturesque wedding canopy and gazebo-perfect for celebrations, and outdoor entertaining. A sweeping circular drive with dual gated entrances creates a grand sense of arrival, leading to oak-shaded grounds, multiple patios, and an expansive resort-style pool with hot tub, ideal for gatherings and leisure alike. Inside, both residences highlight timeless architectural details, including hardwood floors, stone fireplaces, and spacious living areas. A chef's kitchen provides the ideal space for entertaining or everyday comfort, while a private well ensures efficient and sustainable upkeep for the entire property. With its prime location, unmatched amenities, and endless possibilities, 6472 Whitby Rd is more than an estate-it's a destination of its own, offering an extraordinary opportunity to live, entertain, and create.

6472 Whitby, San Antonio
$1,175,000
4 Beds ⋅ 3 Baths ⋅ 2003633 MLS ⋅ ACTIVE Status
Commanding San Antonio skyline views from inside and out from a variety of rooms, patios and elevations! Single-level living and an extensive renovation define this distinctive Oak Hills estate. Set on approximately 0.58 acre beneath mature trees with no mandatory HOA, the 4,136-square-foot home offers four bedrooms, 2.5 baths and substantial system upgrades only minutes from the Medical Center. The renovation extends well beyond finishes, fixtures and appliances and our pictures simply couldn't capture all areas touched. Key items include electrical rewiring and new interior panels, updated plumbing and gas lines, a five-ton Ruud condenser, new ducting and vents, low-E windows and sliding doors, added insulation, new drywall and flooring, cement soffits, roof shingles and decking replaced where needed, a gas fireplace and hydro jet sewer cleanout. Redesigned retaining walls and backyard steps. No details too large or two small! Combine all this with multiple patios, a circular drive, and the expansive grounds still offer room to imagine a pool, sport court, garden or an additional outdoor retreat. To truly grasp the presence and scale of this residence, a private tour is essential. City permits, inspections, testing and supporting documentation will be shared by the seller with offer submissions.

311 E Woodlake Dr, San Antonio
$1,160,000
4 Beds ⋅ 5 Baths ⋅ 1973283 MLS ⋅ NEW Status
A rare offering in San Antonio's prestigious Oak Hills area, this architecturally significant residence brings a distinctly European sensibility to the heart of the Medical Center. Located within a private gated enclave with direct access to Oak Hills Country Club, the home combines striking contemporary design with the ease of a lock-and-leave lifestyle. Created by internationally recognized DDL Architects and SW11 International Custom Home Builders, the residence showcases soaring ceilings, dramatic steel beams, expansive walls of glass, and carefully curated materials, many sourced from Europe. Natural light fills the interiors, while mature oak trees, thoughtfully incorporated into the design, create a seamless connection between architecture and landscape. Designed for both grand entertaining and quiet retreat, the home opens to three intimate courtyard patios surrounded by tranquil water features, fire elements, and inviting gathering spaces. At its center is a year-round indoor smart pool, offering a private wellness experience rarely found in residential properties. The approximately 4,010-square-foot floor plan balances architectural sophistication with everyday comfort, creating spaces that feel equally suited for hosting guests, working remotely, or simply enjoying a peaceful evening at home. Private, secure, and remarkably low-maintenance, this residence is designed for those who value exceptional design, global sophistication, and the freedom to come and go with ease. Opportunities to acquire a home of this caliber and character are exceedingly rare. Experience one of San Antonio's most distinctive contemporary residences by scheduling your private tour today.

4139 Cliff Oaks St, San Antonio
$995,000
1994637 MLS ⋅ ACTIVE Status
URIAH Real Estate Organization is pleased to present 12502 E IH-10, a 2.71 acre commercial land opportunity strategically located along Interstate 10 East in the rapidly growing East San Antonio corridor. Featuring direct frontage on IH-10 and excellent visibility, the property offers convenient access to Loop 1604, FM 1518, and major employment centers throughout Northeast Bexar County. The site benefits from its proximity to Randolph Air Force Base, Joint Base San Antonio, Amazon fulfillment facilities, and the rapidly expanding residential communities throughout Converse, Schertz, and East San Antonio. Continued population growth, new housing developments, and expanding infrastructure in the surrounding area make this an attractive opportunity for investors, developers, and owner-users seeking exposure along one of San Antonio's major transportation corridors. The property is currently improved with a 1,064 square foot manufactured home containing three bedrooms and two bathrooms, providing potential interim income or owner-user functionality while planning future development. Utilities including water and electricity are already available on-site, helping reduce development costs and timelines. Zoned C-2 Commercial and R-6 Residential, the property offers flexibility for a variety of commercial, retail, service-oriented, mixed-use, or residential development opportunities. Potential uses include automotive services, contractor yards, equipment sales, retail storefronts, office-warehouse development, self-storage, convenience retail, RV and trailer sales, or redevelopment into a commercial business park. With strong interstate visibility, flexible zoning, existing improvements, utilities on-site, and immediate access to major highways, 12502 E IH-10 presents a rare opportunity to acquire a versatile commercial site in one of the region's fastest-growing submarkets.

12502 E Interstate 10, San Antonio
$995,000
1994626 MLS ⋅ ACTIVE Status
12502 E IH-10 is a 2.71 acre commercial land opportunity strategically located along Interstate 10 East in the rapidly growing East San Antonio corridor. Featuring direct frontage on IH-10 and excellent visibility, the property offers convenient access to Loop 1604, FM 1518, and major employment centers throughout Northeast Bexar County. The site benefits from its proximity to Randolph Air Force Base, Joint Base San Antonio, Amazon fulfillment facilities, and the rapidly expanding residential communities throughout Converse, Schertz, and East San Antonio. Continued population growth, new housing developments, and expanding infrastructure in the surrounding area make this an attractive opportunity for investors, developers, and owner-users seeking exposure along one of San Antonio's major transportation corridors. The property is currently improved with a 1,064 square foot manufactured home containing three bedrooms and two bathrooms, providing potential interim income or owner-user functionality while planning future development. Utilities including water and electricity are already available on-site, helping reduce development costs and timelines. Zoned C-2 Commercial and R-6 Residential, the property offers flexibility for a variety of commercial, retail, service-oriented, mixed-use, or residential development opportunities. Potential uses include automotive services, contractor yards, equipment sales, retail storefronts, office-warehouse development, self-storage, convenience retail, RV and trailer sales, or redevelopment into a commercial business park. With strong interstate visibility, flexible zoning, existing improvements, utilities on-site, and immediate access to major highways, 12502 E IH-10 presents a rare opportunity to acquire a versatile commercial site in one of the region's fastest-growing submarkets.

12502 E Interstate 10, San Antonio
$995,000
4 Beds ⋅ 3 Baths ⋅ 1946194 MLS ⋅ ACTIVE Status
Stunning traditional home in an exclusive gated community next to Oak Hills Country Club (direct access via golf cart trail), this home offers plenty of space, comfort, and a prime location. Located in the Medical Center, this is the perfect medical professional estate. The open floor plan features high ceilings, crown molding, wood and stone floors, granite kitchen countertops, and two fireplaces. The spacious primary suite includes a sitting area and gorgeous bathroom with a balcony that boasts views of downtown fireworks. The study can easily serve as a fifth bedroom. Enjoy the enclosed backyard with an in-ground pool - perfect for relaxing or entertaining.

4123 Cliff Oaks, San Antonio
$925,000
4 Beds ⋅ 4 Baths ⋅ 2010322 MLS ⋅ NEW Status
Nearly 5,000 square feet of fully reimagined Oak Hills luxury: four oversized bedroom ensuites, each with a private full bath; a true two-up/two-down layout; soaring 20+ foot ceilings; and exceptional indoor-outdoor entertaining, all on nearly half an acre near the South Texas Medical Center. A dramatic great room is anchored by a towering statement fireplace. At the center of the home, the expansive kitchen offers abundant counter space, a breakfast bar and eat-in dining. Oversized bifold glass doors on both sides open fully to two separate decks, flooding the space with natural light and allowing gatherings to flow effortlessly from one deck through the kitchen to the other. The main-level primary retreat is a destination of its own, featuring a built-in electric fireplace with a dramatic floor-to-ceiling surround. The spa-inspired primary bath offers a dedicated dressing area, freestanding air-jetted tub and oversized walk-in shower, while the spectacular room-sized walk-in closet delivers exceptional storage. A second ensuite bedroom is downstairs; two additional ensuite bedrooms and a generous loft/game room are upstairs-an outstanding configuration for multigenerational living, extended guests or anyone who values privacy and flexibility. Additional highlights include a dedicated office, multiple living and dining areas, and a climate-controlled flex room within the garage, ideal for a studio, workshop, creative space or second office. A circular driveway, mature trees, brick-and-stucco exterior, attached two-car garage and dual outdoor decks complete this rare offering. Fully remodeled and created for grand-scale entertaining, 3919 Midvale delivers the space, flexibility and modern finishes rarely found in established Oak Hills.

3919 Midvale Dr, San Antonio
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